| 76 | 2024 Annual Report Abstract We strive to develop innovative nanotechnology-based solutions for broad applications, including early disease diagnosis, targeted drug delivery with reduced side effects, and novel therapeutic approaches. Our vision is to have a significant impact on the future of medicine. Our multidisciplinary research approach integrates researchers from engineering, chemistry, biology, and medicine, consolidating nanomaterial advances with imaging, specific biomarkers, and therapeutics. Molecular CT imaging of cancer using targeted gold nanoparticles. Publications 2023 and 2024 • Adi Anaki, Chen Tzror-Azankot, Menachem Motiei, Tamar Sadan and Rachela Popovtzer. “Impact of Synthesis Methods on the Functionality of Antibody-Conjugated Gold Nanoparticles for Targeted Therapy.” Nanoscale Advances, 2024. • Pnina Shirel Itzhak, Hevroni Yael, Erez Matsree, Hilla Pee'r-Nissan, Shira Ofer Lancman, R Barnea, G Luboshits, Menachem Motiei, Oshra Betzer, Iris Gispan, Rachela Popovtzer, Yaakov Anker, MA Firer, G Yadid. “A Novel Delta Opioid Receptor Specific Peptide Reduces Craving in an Animal Model of Cocaine Seeking.” Addiction Neuroscience, 2024. • Thomas Anchordoquy, Natalie Artzi, Irina V Balyasnikova, Yechezkel Barenholz, Ninh M La-Beck, Jacob S Brenner, Warren CW Chan, Paolo Decuzzi, Agata A Exner, Alberto Gabizon, Biana Godin, Samuel K Lai, Twan Lammers, Michael J Mitchell, S Moein Moghimi, Vladimir R Muzykantov, Dan Peer, Juliane Nguyen, Rachela Popovtzer, Madison Ricco, Natalie J Serkova, Ravi Singh, Avi Schroeder, Anna A Schwendeman, Joelle P Straehla, Tambet Teesalu, Scott Tilden, Dmitri Simberg. “Mechanisms and Barriers in Nanomedicine: Progress in the Field and Future Directions.” ACS Nano, 2024. • Tal Caller, Itai Rotem, Olga Shaihov-Teper, Daria Lendengolts, Yeshai Schary, Ruty Shai, Efrat Glick-Saar, Dan Dominissini, Menachem Motiei, Idan Katzir, Rachela Popovtzer, Merav Nahmoud, Alex Boomgarden, Crislyn D’Souza-Schorey, Nili Naftali-Shani, Jonathan Leor. “Small Extracellular Vesicles from Infarcted and Failing Heart Accelerate Tumor Growth.” Circulation, 2024. • Gilad Halpert, Omer Moskovitch, Adi Anaki, Tal Caller, Oleg Gendelman, Abdulta Watad, Ruty Shai, Rachela Popovtzer, Haward Amital. “AB0076 the Therapeutic Potential of Circulating Autologous Tissue Homing Extracellular Vesicles for the Management of Rheumatoid Heumatoid Aathritis Patients.” Annals of the Rheumatic Diseases, 2023. • Yoray Sharon, Menachem Motiei, Chen Tzror-Azankot, Tamar Sadan, Rachela Popovtzer, Eli Rosenbaum. “A ‘Golden’ Alternative for Prevention of Cisplatin Nephrotoxicity in Bladder Cancer.” Cancer Nanotechnolgy, 2023. Prof. Rabin Yitzhak Department of Physics Soft and Biological Matter Research Areas • Biophysics • Polymer physics • Soft condensed matter (polymers, gels, liquid crystals) and disordered solids • Interfaces and confined systems • Theoretical physics • Geometrical methods in physics • Statistical mechanics Abstract Prof. Rabin Yitzhak performs theoretical studies of APD (All Particles are Different) fluids and solids, Microbiome-host adaptation, Bacterial division, Reactions and phase separation in active systems, Scale-dependent viscoelasticity, NPC (nuclear pore complex) morphology. Publications 2023 and 2024 • Harsh Vashistha, Joanna Jammal-Touma, Kulveer Singh, Yitzhak Rabin, Hanna Salman. “Bacterial Cell-Size Changes Resulting From Altering the Relative Expression of Min Proteins.” Nature Communications, 2023. • Ajoy Maji, Kinjal Dasbiswas, Yitzhak Rabin. “Shape Transitions in Network Model of Active Elastic Shells.” Soft Matter, 2023. Dr. Radovsky Gal HR-TEM Publications 2023 and 2024 • Sri Harsha Akella, Shalev Blanga, Melina Zysler, Gal Radovsky, Malachi Noked. “The Role of Zinc Triflate Additive for Improved Electrochemical Performance of Nickel-Rich Layered Oxide Lithium Battery Cathode via Suppression of Interfacial Parasitic Reactions.” Journal of The Electrochemical Society, 2024.
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