| 86 | 2024 Annual Report “Monte Carlo-Simulated Annealing and Machine Learning-Based Funneled Approach for Finding the Global Minimum Structure of Molecular Clusters.” ACS Omega, 2023. • Ori Licht, Darío Barreiro‐Lage, Patrick Rousseau, Alexandre Giuliani, Aleksandar R Milosavljevi , Avinoam Isaak, Yitzhak Mastai, Amnon Albeck, Raj Singh, Vy TT Nguyen, Laurent Nahon, Lara Martínez‐ Fernández, Sergio Díaz‐Tendero, Yoni Toker. “Peptide Bond Formation in the Protonated Serine Dimer Following Vacuum UV Photon‐Induced Excitation.” Angewandte Chemie, 2023. • Klavs Hansen, Ori Licht, Adeliya Kurbanov, Yoni Toker. “Cascade Infrared Thermal Photon Emission.” The Journal of Physical Chemistry A, 2023. • Yehuda Ben Shabo, Adeliya Kurbanov, Claus-Dieter Schröter, Robert Moshammer, Holger Kreckel, Yoni Toker. “Velocity Map Imaging with No Spherical Aberrations.” Physical Chemistry Chemical Physics, 2023. • Ori Licht, Maria Nihamkin, Mirit Anaby, Patrick Rousseau, Alexandre Giuliani, Aleksandar Milosavljevic, Raj Singh, Vy Nguyen, Laurent Nahon, Yoni Toker. “Vacuum UV Studies of Protonated Serine Clusters.” Journal of Physics B: Atomic, Molecular and Optical Physics, 2023. • Ori Licht, Darío Barreiro‐Lage, Patrick Rousseau, Alexandre Giuliani, Aleksandar R Milosavljevi , Avinoam Isaak, Yitzhak Mastai, Amnon Albeck, Raj Singh, Vy TT Nguyen, Laurent Nahon, Lara Martínez‐ Fernández, Sergio Díaz‐Tendero, Yoni Toker. “Peptide Bond Formation in the Protonated Serine Dimer Following Vacuum UV Photon‐Induced Excitation.” Angewandte Chemie, 2023. Prof. Tzur Amit The Mina & Everard Goodman Faculty of Life Sciences The Laboratory for the Study of the Division and Growth Cycle in Mammalian Cells Research Areas • The mammalian cell cycle • Cell growth and size homeostasis of proliferating cells Abstract The cell cycle is a remarkably unidirectional and controlled process that allows for the preservation of genetic material. For the cell to maintain its size and function, it must grow during its life cycle in a way that leads to its doubling. Therefore, it is assumed that there is an active connection between the life cycle of a dividing cell and its growth cycle. This connection has not been characterized in mammalian cells. Still, it is likely to occur in the G1 phase of the cell cycle, a phase in which the cell examines growth signals from the environment and determines whether to proceed to another division cycle or to stop and/or differentiate. The G1 phase is characterized by cell growth, but the molecular basis linking this metabolic process to the cell cycle is unclear. It is also known that there is significant variability in the length of the G1 phase between cells from different tissue sources, ranging from a few hours to dozens of hours, even under optimal growth conditions. The source of this variability and its relation to cell growth is unknown. The laboratory studies the division and growth cycle and the connection between these pathways in mammalian cells. This research combines optical and other methods to track living cells' division and growth cycle simultaneously. From these measurements, it is possible to learn if, when, and how the growth and division cycles are intertwined. Additionally, various quantitative molecular and biochemical approaches will assist in the molecular mapping of the G1 phase concerning cell growth and the study of controlled protein degradation and its importance in regulating this phase. The laboratory also develops and applies advanced micrometric methods for identifying and characterizing cell cycle proteins that have not yet been studied. Dr. Vestfrid Yulia E-SEM, HR-SEM Publications 2023 and 2024 • Elena Markevich, Gregory Salitra, Yulia Vestfrid, Michal Afri, Suresh Sriramulu, Andrew Sharratt, Karthik Venkataraman, Doron Aurbach. “CF3-Substituted Ethylene Carbonates for High-Voltage/ High-Energy Rechargeable Lithium Metal–LiNi0.8Co0.1Mn0.1O2 Batteries.” ACS Applied Materials & Interfaces, 2024. Prof. Weiss Shimon Department of Physics BIU Department of Chemistry and Biochemistry UCLA The Laboratory for Nanosensors in Brain Research Research Areas • Single-molecule detection and spectroscopy • Dynamic structural/molecular biology • Protein folding, protein-protein and protein-DNA interactions • Novel bio-nano-technology probes, semiconductor nanocrystals, quantum
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